Trachoma and Conjunctivitis

Trachoma and Inclusion Conjunctivitis

Effect of bacterial secondary infection in an animal model of trachoma.

In trachoma the interaction between chronic chlamydial and acute bacterial conjuntivitis has been suggested as important in determining the severity of disease and, therefore, blindness. We investigated the effect of acute conjunctival infection with each of three common human pathogens, Haemophilus influenzae, Haemophilus aegyptius , and Streptococcus pneumoniae, in a model of trachoma establi...

Experiments on the Cultivation of so Called Trachoma Bodies

1. An organism was isolated and studied in pure cultures from cases of conjunctivitis accompanied by the so called trachoma body inclusions, as well as from a case of old trachoma without inclusions. 2. This organism was not found in the cultures made from other forms of conjunctivitis in which the inclusions were absent. 3. The organism presents the morphological features characteristic of so ...

Comparative Therapeutic Field Trials of G.s. 2989 and Oxytetracycline in Trachoma.

G.S. 2989 Hcl (Pfizer) is a new tetracycline derivative without any generic name. In a cinico-cytological study by Nema, Nath, Bal, and Shukla (1964) on 48 trachomatous cases treated by G.S. 2989 Hcl (025 per cent. in oil) the antibiotic was found quite effective against trachoma and associated bacterial conjunctivitis. It was observed that the drug could produce 66-7 per cent. cure of trachoma...

Trachoma: the forgotten cause of blindness.

Trachoma, the second leading cause of blindness world wide, continues to be hyperendemic in many areas of Africa, Asia, and the Middle East. Caused by an ocular infection with Chlamydia trachomatis, this chronic conjunctivitis results in more blindness than any other infectious eye disease. Once endemic in most countries, trachoma has largely disappeared from Europe and the Americas. Because of...

Trachoma: an Ancient and Contemporary Scourge

Trachoma is an ancient yet contemporary scourge. It is a specific kerato-conjunctivitis caused by certain serovars of Chlamydia trachomatis. It affects an estimated 84 million people and remains the commonest communicable cause of blindness in 6 million people. WHO has introduced the SAFE strategy which needs to be implemented with more determination in Nigeria if the level of trachoma blindnes...